Keywords
food safety
dairy
antibiotic residues
How to Cite
Abstract
Antibiotic residues in pasteurized milk have been report in region countries. The demand of fluid milk is supplier with local and imported products. Due to the above, our purpose is to explore antibiotic residues in ultra-pasteurized milk in the metropolitan area of Guatemala. Beta-lactam, tetracycline, and sulfonamide antibiotics were screening using the rapid colloidal gold immunochromatographic technique with the MilkSafe™ 3BTS test. A total of 258 liters of milk at room temperature, offered to the public in 78 supermarkets, were used in this study. The availability of the eight brands varied by site at the time of sampling, causing differences in the quantities of units purchased. All samples (100 %) resulted in the absence of the MilkSafe™ 3BTS test residues. The possible reasons for obtaining results below the maximum residue limits (MRL) and the implications of these findings in the surveillance system for veterinary residues in milk for human consumption are discussing.
References
Ashuo, A., Wenjia, Z., Jingjie, F., Yang, T., Yu, L., Lui, W., Yang, L., Mari, G.M., Jiang, H. (2020). High Throughput Detection of Antibiotic Residues in Milk by Time-Resolved Fluorescence Immunochromatography Based on QR Code. Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment 37 (9): 1481–90. https://doi.org/10.1080/1 9440049.2020.1778192.
Bacanlı, M., Nurşen, B. (2019). Importance of Antibiotic Residues in Animal Food. Food and Chemical Toxicology 125: 462–66. https://doi.org/10.1016/j.fct.2019.01.033.
Baynes, R.E., Lyman, R., Anderson, K.L., Brownie, C.F. (1999). A Preliminary Survey of Antibiotic Residues and Viable Bacteria in Milk from Three Caribbean Basin Countries. Journal of Food Protection 62 (2): 177–80. https://doi.org/10.4315/0362-028X-62.2.177.
Bermudez, O.I., Hernandez, L., Mazariegos, M., Solomons, N.W. (2008). Secular Trends in Food Patterns of Guatemalan Consumers: New Foods for Old. Food and Nutrition Bulletin 29 (4): 278–87. https://doi.org/10.1177/156482650802900404.
Byzova, N.A., Zvereva, E.A., Zherdev, A.V. , Dzantiev, B.B. (2011). Immunochromatographic Technique for Express Determination of Ampicillin in Milk and Dairy Products. Applied Biochemistry and Microbiology 47 (6): 627–34. https://doi.org/10.1134/S0003683811060032.
CHR Hansen. n.d. MilkSafeTM 3BTS.
Codex Alimentarius. (2011). Leche y Productos Lácteos Leche y Productos Lácteos. CODEX Alimentarius. http://www.fao.org/3/i2085s/i2085s.pdf.
Coguanor. (2005). COGUANOR. Diario Oficial 14 de Agosto de 1986.
Cruz, M., Pérez-Domínguez, M., Velázquez, F. (1986). Frecuencia de La Contaminación de La Leche Disponible En El Valle de México Con Estreptomicina, Tetraciclina y Penicilina. Salud pública de México 28 (4): 438–42.
Du, B., Wen, F., Zhang, Y., Zheng, N., Li, S., Li, F., Wang, J. (2019). Presence of tetracyclines, quinolones, lincomycin and streptomycin in milk. Food Control, Volume 100, Pages 171-175, ISSN 0956-7135, https://doi.org/10.1016/j.foodcont.2019.01.005.
Durel, L., Gallina, G. and Pellet, T. (2019). Assessment of Ceftiofur Residues in Cow Milk Using Commercial Screening Test Kits. Veterinary Record Open 6 (1): 1–7. https://doi.org/10.1136/vetreco-2018-000329.
Dweba, C.C., Zishiri, O.T. El Zowalaty, M.E. (2018). Methicillin-Resistant Staphylococcus Aureus: Livestock-Associated, Antimicrobial, and Heavy Metal Resistance. Infection and Drug Resistance 11: 2497–2509. https://doi.org/10.2147/IDR.S175967.
Food and Agriculture Organization of the Nations (FAO). (2019). Chapter 7. Dairy and Dairy Products. OECD-FAO Agricultural Outlook 2019-2028, 180–89. http://www.fao.org/3/CA4076EN/CA4076EN_Chapter7_Dairy.pdf.
Food and Agriculture Organization of the Nations (FAO) and World Health Organization (OMS). (2015). Maximum Residue Limits (MRLs) and Risk Management Recommendations (RMRs) for residues of veterinary drugs in foods. FAO.
Food and Agriculture Organization of the Nations (FAO). (2023). Food Balances (2010-). In: FAOSTAT. Rome. [Cited September 2023].https://www.fao.org/faostat/en/#data/FBS.
Gutiérrez Tolentino, R., Noa Pérez, M., Díaz González, G., Vega y León, S., González López, M., Prado Flores, G. (2005). Determination of the presence of 10 antimicrobial residues in Mexican pasteurized milk. Interciencia, 30(5), 291-294.
Ilievski, D., Trajkovska, B., Kochoski, L. (2022). Use of screening tests for ceftiofur in evaluation of raw milk safety. KNOWLEDGE-International Journal, 52(3), 381–384. Retrieved from https://ikm.mk/ojs/index.php/kij/article/view/5201.
Jáuregui, R., Celis, E. (2018). Prevalencia de Antibióticos Residual es en Leche Cruda de Bovino en Finca en el Departamento de Chiquimula. Dirección General de Investigación. Universidad de San Carlos de Guatemala. http://forschungsunion.de/pdf/industrie_4_0_umsetzungsempfehlungen.pdf%0Ahttps://www.dfki.de/fileadmin/user_upload/import/9744_171012-KI-Gipfelpapier-online.pdf%0Ahttps://www.bitkom.org/ sites/default/files/ pdf/Presse/Anhaenge-an-PIs/ 2018/180607 -Bitkom.
Jarquin, C., Alvarez, D., Morales, O., Morales, A. J., López, B., Donado, P., Valencia, M.F., Arévalo A., Muñoz, F., Walls, I., Doyle, M.P., Alali, W.Q. (2015). Salmonella on raw poultry in retail markets in Guatemala: Levels, antibiotic susceptibility, and serovar distribution. Journal of food protection, 78(9), 1642-1650.
Kellnerová, E., Navrátilová, P., Borkovcová, I. (2015). Effect of pasteurization on the residues of tetracyclines in milk. Acta Veterinaria Brno, 83(10), 21-26.
Lee, M. H., Lee, H. J., Ryu, P.D. (2001). Chemical and Antibiotic Resides. Asian-Australian Journal of Animal Science.
Leiva, A., Méndez, G., Rodríguez, C., Molina, A., Granados-Chinchilla, F. (2019). Chemical Assessment of Mycotoxin Contaminants and Veterinary Residues in Costa Rican Animal Feed. International Journal of Food Contamination 6 (1): 1–26. https://doi.org/10.1186/s40550-019-0075-8.
Lozano, M., Arias, D. (2008). Residuos de fármacos en alimentos de origen animal: panorama actual en Colombia. Revista Colombiana de ciencias pecurias, 21(1), 121-135.
Máttar, S., Calderón, A., Sotelo, D., Sierra, M., Tordecilla, G. (2009). Detección de antibióticos en leches: un problema de salud pública. Revista de Salud Pública, 11, 579-590.
Monge, R., Arias, M.L., Ellner, R. (1993). Contamination of Bovine Milk with Residues of Inhibitory Substances in Costa Rica. Revista de Biología Tropical, 41 (3 B): 855–56.
Rahman, S., Hassan, M. M., Chowdhury, S. (2021) Determination of antibiotic residues in milk and assessment of human health risk in Bangladesh, Heliyon, 7(8). https://doi.org/10.1016/j.heliyon.2021.e07739.
Ramay, B.M., Claudell, M.A., Cordón-Rosales, C., Archilar, L.D., Palmer, G.H., Jarquin, C., Moreno, P., McCracken, J.P., Rosenkrantz, L., Amram, O., Omulo, S., Call, D.R. (2020). Antibiotic Use and Hygiene Interact to Influence the Distribution of Antimicrobial-Resistant Bacteria in Low-Income Communities in Guatemala. Scientific Reports 10 (1): 1–10. https://doi.org/10.1038/s41598-020-70741-4.
Redwan Haque, A., Manobendro Sarker, R. D., Abul K. A., Mehedi, H. (2021). A Review on Antibiotic Residue in Foodstuffs from Animal Source: Global Health Risk and Alternatives. International Journal of Environmental Analytical Chemistry 00 (00): 1–18. https://doi.org/10.1080/03067319.2021.1912334.
Reglamento Técnico Centroamericano. (2015). Reglamento Técnico Centroamericano RTCA 67.04.71:14 Productos Lácteos. Cremas (Natas) y Cremas (Natas preparadas). RTCA.
Ruano, S. (1996). Guatemala: Situacion General de la Producción. In Latin America Livestock Regional Assessment Workshop: San José, Costa Rica, April 15-18, 1996 (p. 65). IICA.
Sachi, S., Jannatul, F., Mahmudul H.S., Azizul, K.H.S.M. (2019). Antibiotic Residues in Milk: Past, Present, and Future. Journal of Advanced Veterinary and Animal Research 6 (3): 315–32. https://doi.org/10.5455/javar.2019.f350.
Schlemper, V., Sachet, A.P. (2017). Antibiotic residues in pasteurized and unpasteurized milk marketed in southwest of Paraná, Brazil. Ciência Rural, 47.
Snively-Martinez, A.E. (2019). Ethnographic decision modeling to understand smallholder antibiotic use for poultry in Guatemala. Medical Anthropology, 38(3), 295-310.
Svenson, E.L., Tun, R., Conway, J.H., Legenza, L., Svenson, J.M., Duffy, S., Svenson, J.E. (2021). A one health approach to compare self-prescribed antibiotic use across rural and semi-urban populations in San Lucas Tolimán, Guatemala. Journal of Health Care for the Poor and Underserved, 32(4), 1798-1817.
Valdés-Ramos, R., Mendoza, I., Solomons, N.W. (2001). Concordance of Dietary Intake with the ‘Dietary Guidelines for Americans’ among Adults in Rural ‘Santa Rosa’ Province, Guatemala. Nutrition Research 21 (1–2): 81–91. https://doi.org/10.1016/S0271-5317(00)00249-9.
Valdez-Sandoval, J. (2023). Marketing digital en la Industria Láctea de Guatemala: Una evaluación de la presencia, impacto y análisis de contenido en facebook, instagram y twitter. Ciencia Latina Revista Científica Multidisciplinar, 7(2), 9179-7201.
Velázquez, F., Pérez, M., González, R. (1980). Investigación de Residuos de Antibióticos En Leche Pasteurizada y Envasada Que Se Consume En El Área Metropolitana. Salud Publica de Mexico 22 (1): 91–99.
Vranješ, A. P., Popović, M., Jevtić, M. (2015). Raw Milk Consumption and Health. Srpski Arhiv Za Celokupno Lekarstvo 143 (1–2): 87–92. https://doi.org/10.2298/SARH1502087P.
World Population Review (2023). Milk consumption by county: Guatemala.https://worldpopulationreview.com/country-rankings/milk-consumption-by-country
Zhang, Y.D., Zheng, N., Han, R. W., Zheng, B. Q., Yu, Z. N., Li, S. L., Zheng, S. S., Wang, J. Q. (2014). Occurrence of tetracyclines, sulfonamides, sulfamethazine and quinolones in pasteurized milk and UHT milk in China’s market, Food Control, 36(1):238-242, ISSN 0956-7135, https://doi.org/10.1016/j.foodcont.2013.08.012.
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